Optically active amines by enzyme-catalyzed kinetic resolution.

[摘要]：Chiral amines were resolved by an enzyme-catalyzed kinetic resoln. Key steps are the selective acylation of one enantiomer with iso-Pr methoxyacetate, sepn. of the resulting amide from the unreacted antipode, and finally amide hydrolysis. The process proceeds with excellent selectivity and is highly flexible with regard to substrates.

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