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Copper-Mediated Cyanation of Aryl Halide with the Combined Cyanide Source

  作者 ZHANG GUOYING; REN XINYI; CHEN JIANBIN; HU MAOLIN; CHENG JIANG  
  选自 期刊  Organic Letters;  卷期  2011年13-19;  页码  5004-5007  
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[摘要]A simple copper-mediated cyanation of aryl halide with the combination of ammonium bicarbonate and N,N-dimethylformamide as a cyanide source is achieved, providing nitriles in moderate to good yields. This new approach represents an exceedingly practical and safe method for the synthesis of aryl nitriles.

 
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