Regioselective synthesis of either 1H- or 2H-1,2,3-triazoles via Michael addition to a,b-unsaturated ketones.

[摘要]：The Michael reaction of NH-1,2,3-triazole (I) with a,b-unsatd. ketones was studied. 1H-1,2,3-triazolyl-ketones were selectively generated when I was combined neat with a variety of enones. The use of aprotic solvents with catalytic base gave the corresponding 2H-regioisomers. Together, these 2 protocols provide direct access to either N(1)- or N(2)-substituted 1,2,3-triazolyl ketone regioisomers.

[全文传递流程]：

一般上传文献全文的时限在1个工作日内