Enantioselective synthesis of the PPARa agonist (R)-K-13675 via (S)-2-hydroxybutyrolactone. [Erratum to document cited in CA149:200809].
[摘要]:The sp. rotation value stated for (R)-2-[3-({benzoxazol-2-yl[3-(4-methoxyphenoxy)propyl]amino}methyl)ph enoxy]butanoic acid[(R)-K-13675, 1] was incorrect. The correct value is: [a]D25+17.0(c 1.00,CHCl3).
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