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A Periplasmic Reducing System Protects Single Cysteine Residues from Oxidation

  作者 Depuydt, M; Leonard, SE; Vertommen, D; Denoncin, K; Morsomme, P; Wahni, K; Messens, J; Carroll, KS; Collet, JF  
  选自 期刊  Science;  卷期  2009年326-5956;  页码  1109-1111  
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[摘要]The thiol group of the amino acid cysteine can be modified to regulate protein activity. The Escherichia coli periplasm is an oxidizing environment in which most cysteine residues are involved in disulfide bonds. However, many periplasmic proteins contain

 
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