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Magnetic/Silica Nanocomposites as Dual-Mode Contrast Agents for Combined Magnetic Resonance Imaging and Ultrasonography

  作者 Malvindi, MA; Greco, A; Conversano, F; Figuerola, A; Corti, M; Bonora, M; Lascialfari, A; Doumari, HA; Moscardini, M; Cingolani, R; Gigli, G; Casciaro, S; Pellegrino, T; Ragusa, A  
  选自 期刊  ADVANCED FUNCTIONAL MATERIALS;  卷期  2011年21-13;  页码  2548-2555  
  关联知识点  
 

[摘要]A simple and efficient method for synthesizing a range of hybrid nanocomposites based on a core of silica nanospheres (160, 330, and 660 nm in diameter) covered by an outer shell of superparamagnetic nanoparticles, either iron oxide or heterodimeric FePt-iron oxide nanocrystals, is presented. The magnetic and ultrasound characterization of the resulting nanocomposites shows that they have great potential as contrast agents for dual-mode imaging purposes, combining magnetic resonance imaging (MRI) and ultrasonography (US).

 
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