【文章名】Sterically demanding, zwitterionic trialkylphosphonium sulfonates as air-stable ligand precursors for efficient palladium-catalyzed cross-couplings of aryl bromides and chlorides.
Sterically demanding, zwitterionic trialkylphosphonium sulfonates as air-stable ligand precursors for efficient palladium-catalyzed cross-couplings of aryl bromides and chlorides.
作者
Brown, William S.;Boykin, D'Ariel D.;Sonnier, M. Quentin, Jr.;Clark, William D.;Brown, Fallon V.;Shaughnessy, Kevin H.;
[摘要]：3-(Di-tert-butylphosphonium)propane sulfonate (DTB-PPS) and 3-(diadamantylphosphonium)propane sulfonate (DAPPS) are air-stable pre-ligands for aq.-phase palladium-catalyzed cross-coupling reactions. Both DTBPPS and DAPPS gave active catalysts for the Sonogashira coupling of aryl bromides at room temp. and of 4-chloroanisole at 80? These ligands also gave effective catalysts for the aq.-phase Suzuki coupling of aryl bromides at room temp.
