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Spheres without Influence: Dissociating In Vitro Self-Renewal from Tumorigenic Potential in Glioma

  作者 Read, TA; Wechsler-Reya, RJ  
  选自 期刊  Cancer Cell;  卷期  2012年21-1;  页码  1-3  
  关联知识点  
 

[摘要]The capacity for self-renewal is thought to be a critical property of tumor-initiating cells. This capacity is often associated with the ability to generate spheres in vitro. In this issue of Cancer Cell, Barrett et al. show that cells lacking sphere-forming ability can still be very efficient at propagating tumors.

 
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