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Planarian Hh Signaling Regulates Regeneration Polarity and Links Hh Pathway Evolution to Cilia

  作者 Rink, JC; Gurley, KA; Elliott, SA; Alvarado, AS  
  选自 期刊  Science;  卷期  2009年326-5958;  页码  1406-1410  
  关联知识点  
 

[摘要]The Hedgehog (Hh) signaling pathway plays multiple essential roles during metazoan development, homeostasis, and disease. Although core protein components are highly conserved, the variations in Hh signal transduction mechanisms exhibited by existing mode

 
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