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Cytotoxic Triterpenoids from Maytenus retusa

  作者 Oramas-Royo, SM; Chavez, H; Martin-Rodriguez, P; Fernandez-Perez, L; Ravelo, AG; Estevez-Braun, A  
  选自 期刊  Journal of natural products;  卷期  2010年73-12;  页码  2029-2034  
  关联知识点  
 

[摘要]Seven new triterpenoids (1-7) and 36 known compounds were isolated from the root bark of Maytenus retusa. Their structures were determined by ID and 2D spectroscopic studies. Several compounds were evaluated for their cytotoxicity against the human tumor cell lines HL-60 and MCF-7. Some of them were cytotoxic, with IC50 values ranging between 0.2 and 4.7 mu M.

 
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