An Efficient Protocol for Multicomponent Synthesis of Spirooxindoles Employing L-Proline as Catalyst at Room Temperature

[摘要]：An efficient three-component one-pot synthesis of medicinally important spirooxindoles is described by the reaction of isatin, malononitrile/ethyl cyanoacetate, and dimedone/barbituric acid using L-proline as catalyst in ethanol at room temperature. This approach is convenient, mild, and affords the products in high yields without the use of chromatography.

[全文传递流程]：

一般上传文献全文的时限在1个工作日内