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Regioselective double nucleophilic addition reaction leading to the synthesis of b-lactams.

  作者 Takahashi, Atsushi;Kawai, Shiho;Hachiya, Iwao;Shimizu, Makoto;  
  选自 期刊  Heterocycles;  卷期  2008年76-1;  页码  203-208  
  关联知识点  
 

[摘要]b-Lactams were prepd. in a regio- and stereoselective manner using the double nucleophilic addn. of ketene silyl acetals and ketene silyl thioacetals to a,b-unsatd. imines followed by base-promoted cyclization. An attempted approach to 2-arylcarbapenem is also described.

 
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