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Facile access to 2-arylindolines and 2-arylindoles by microwave-assisted tandem radical cyclization.

  作者 Prediger, Inga;Weiss, Torsten;Reiser, Oliver;  
  选自 期刊  Synthesis;  卷期  2008年-14;  页码  2191-2198  
  关联知识点  
 

[摘要]A new route providing access to 2-arylindoles was developed. The synthesis consists of a tin-mediated tandem radical cyclization of appropriate precursors to form 2,3-disubstituted dihydroindoles, which in turn are oxidized to yield the corresponding 2-arylindoles. The reactions proceed smoothly under microwave irradn., furnishing the desired products in good yields.

 
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