Insight into the reactive form of the anticancer agent iproplatin

[摘要]：

The reaction of iproplatin with reduced glutathione at different mole ratios yielded cis-di(isopropylamine)chloro-glutathionatoplatinum(H), not the expected cis-dichloro-species, indicating a mode of action of this anticancer agent that is different from that of cis-diamminedichloroplatinum(II). (C) 2007 Elsevier Masson SAS. All rights reserved.

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