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Cancer cell detection based on the interaction between an anticancer drug and cell membrane components

  作者 CHANDRA PRANJAL; NOH HUIBOG; SHIM YOONBO  
  选自 期刊  Chemical Communications;  卷期  2013年49-19;  页码  1900-1902  
  关联知识点  
 

[摘要]Simple and general cancer cell detection methods are required in point-of-care diagnostics. Herein, the interaction between an anticancer drug, daunomycin, and cancer cell membrane components has been studied using an aptamer probe immobilized on a conducting polymer-gold nanoparticle composite film through electrochemical and fluorescence methods and applied to the quantitative detection of cancer cells. The developed method differentiates between cancerous and non-cancerous cells effectively.

 
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