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ALKYNE-ACETAL CYCLISATION REACTIONS MEDIATED BY FORMIC ACID; 3-ACYLATED-2,5-DIHYDROFURANS AND RELATED OXYGEN AND NITROGEN HETEROCYCLES

  作者 CUTHBERTSON JAMES D; GODFREY ANDREW A; UNSWORTH WILLIAM P; TAYLOR RICHARD J K  
  选自 期刊  Heterocycles;  卷期  2012年84-2;  页码  1013-1021  
  关联知识点  
 

[摘要]The utility of formic acid for the cyclisation of alkyne omega-acetals is described; the scope and limitations of this process are outlined and a range of acylated heterocyclic building blocks (2,5-dihydrofurans, 2,5-dihydro-1H-pyrroles, tetrahydropyridines, 2H-chromenes, 1,2-dihydroquinolines and benzoxepin5-(2H)-ones) are reported.

 
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