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Palladium-Catalyzed Cross-Coupling Reaction of AlArEt2(THF) with Aryl Bromides

  作者 SHU WANTING; ZHOU SHUANGLIU; GAU HANMOU  
  选自 期刊  Synthesis;  卷期  2009年-23;  页码  4075-4081  
  关联知识点  
 

[摘要]Efficient cross-coupling reactions of aryl bromides with AlArEt2(THF) (Ar = Ph, 4-MeC6H4, 4-MeOC6H4, 4-Me3SiC6H4, or 2-naphthyl) catalyzed by a catalytic system of 1 mol% Pd(OAc)(2) and 2 mol% PCy3 furnish aryl-aryl coupling products. The system works well for a wide range of aryl bromides regardless of the electronic or steric nature of the substituent on the aryl bromides.

 
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