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A New Histone at the Centromere?

  作者 Foltz, DR; Stukenberg, PT  
  选自 期刊  Cell;  卷期  2012年148-3;  页码  394-396  
  关联知识点  
 

[摘要]The centromere is a classic system to study epigenetic specification, and most research has focused on a specialized histone variant, CENP-A, that is required for kinetochore assembly. Now Nishino et al. reveal a new level of complexity for centromeric chromatin, by showing that the kinetochore complex CENP-T-W-S-X shares structural and functional properties with canonical histones.

 
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