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Directing Lung Endoderm Differentiation in Pluripotent Stem Cells

  作者 Kadzik, RS; Morrisey, EE  
  选自 期刊  Cell Stem Cell;  卷期  2012年10-4;  页码  355-361  
  关联知识点  
 

[摘要]The lung is composed of numerous epithelial lineages that arise from the anterior foregut endoderm. This review discusses how insights into the signaling mechanisms that regulate lung endoderm specification and subsequent differentiation have recently been exploited to direct differentiation of hESCs/iPSCs into expandable lung progenitors.

 
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