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Stereoselective Synthesis of Disubstituted Butadienes via Copper-Mediated Coupling of Alkenyl Silanes

  作者 BLACKWELL DAVID T; GALLOWAY WARREN R J D; SPRING DAVID R  
  选自 期刊  SYNLETT;  卷期  2011年-15;  页码  2140-2144  
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[摘要]A strategy is described for the stereoselective synthesis of substituted (E)-, (Z)-, and alpha-disubstituted butadienes from terminal alkynes by the copper-mediated coupling of geometrically-defined alkenyl silanes. Proof-of-concept results that demonstrate the feasibility of this approach are presented.

 
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