Facile Synthesis of Substituted Ethyl 2-(Chloromethyl)-2-hydroxy-2H-1-benzopyran-3-carboxylates
[摘要]:Ethyl 2-(chloromethyl)-2-hydroxy-2H-chromene-3-carboxylates 2a-2j have been synthesized by reaction of substituted salicylaldehydes with ethyl 4-chloro-3-oxobutanoate, in the presence of piperidine in CH2Cl2 at room temperature, in good yields.
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