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Access to Ynamides via CuO-Mediated Oxidative Amidation of Alkynes

  作者 TONG XIAOGANG; NI GUANGHUI; DENG XU; XIA CHENGFENG  
  选自 期刊  SYNLETT;  卷期  2012年-17;  页码  2497-2500  
  关联知识点  
 

[摘要]Copper(II) oxide mediated the direct coupling of terminal alkynes and amides by way of C-H functionalization to afford ynamides as useful building blocks. Some alkali halides such as KCl were discovered to play a key role as additive in the coupling reaction, while other salts could suppress the formation of products.

 
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