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Solvent-Free Chemoselective Cyanation of alpha,alpha-Dibromoacetophenones Using Potassium Hexacyanoferrate(II) as an Eco-Friendly Cyanide Source

  作者 ZHAO ZHOUXING; LI ZHENG  
  选自 期刊  European Journal of Organic Chemistry;  卷期  2010年-28;  页码  5460-5463  
  关联知识点  
 

[摘要]A chemoselective route for the synthesis of 2-aryl-3,3-dibromoacrylonitriles by solvent-free cyanation of alpha,alpha-dibromoacetophenones by using potassium hexacyanoferrate(II) as an eco-friendly cyanide source is developed The merits of this procedure include avoiding the use of a strong toxic cyanide source, a catalyst, and volatile organic solvents and the high yields of the products

 
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