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[摘要]：The palladium-catalysed direct 5-arylation of furan or thiophene derivatives bearing CH2NHR substituents (with R = COMe or CO(2)tBu) generally proceeds in good yields by using a catalysts loading of only 0.1-2 mol-%. A wide range of functions such as acetyl, propionyl, formyl, ester, nitrite, trifluoromethyl or fluor on the aryl bromide is tolerated. Higher yields were generally obtained in the presence of electron-deficient aryl bromides than with electron-rich aryl bromides |
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