Total Synthesis of (+)-Seimatopolide A

[摘要]：The first enantioselective total synthesis of a polyhydroxylated macrolide, (+)-seimatopolide A, was achieved. The key reactions, Sharpless asymmetric dihydroxylation, Yamaguchi esterification, and ring-closing metathesis, provided easy access to the target molecule from L-aspartic acid. Further, the absolute stereochemistry of the natural product has also been revised.

[全文传递流程]：

一般上传文献全文的时限在1个工作日内