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Total Synthesis of (?-Murrayazoline.

  作者 Ueno, Akiko;Kitawaki, Takafumi;Chida, Noritaka;  
  选自 期刊  Organic Letters;  卷期  2008年10-10;  页码  1999-2002  
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[摘要]The total synthesis of (?-murrayazoline (I) is described. The characteristic hexa-heterocyclic structure of I was constructed by a combination of the intramol. Friedel-Crafts-type Michael addn. and Pd-catalyzed C-O coupling reactions. The N-substituted carbazole component was synthesized in one pot by the double N-arylation of a sterically hindered amine with a dibromobiphenyl deriv.

 
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