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Branched peptide boronic acids (BPBAs): a novel mode of binding towards RNA

  作者 ZHANG WENYU; BRYSON DAVID I; CRUMPTON JASON B; WYNN JESSICA; SANTOS WEBSTER L  
  选自 期刊  Chemical Communications;  卷期  2013年49-24;  页码  2436-2438  
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[摘要]We report branched peptide boronic acids (BPBAs) that bind to RRE IIB from an on-bead high-throughput screening of a 3.3.4-library (46 656 compounds). We demonstrate that boronic acids are tunable moieties that afford a novel binding mode towards RNA.

 
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