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Efficient Synthesis of Phenanthridines Using Hendrickson Reagent Initiated Cascade Reaction under Mild Conditions

  作者 XI JIE; DONG QINGLI; LIU GUANSAI; WANG SHAOZHONG; CHEN LIN; YAO ZHUJUN  
  选自 期刊  SYNLETT;  卷期  2010年-11;  页码  1674-1678  
  关联知识点  
 

[摘要]A number of variously substituted phenanthridines have been synthesized using the newly developed methodology under mild conditions. The Hendrickson reagent initiated cascade annulation, which is composed of a mild conversion of stable amide precursor to highly reactive imido-carbonium intermediate and a subsequent intramolecular Friedel-Crafts reaction, successfully served as the key method.

 
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