An Efficient, Simple, and Scaleable Domino Reaction to Diverse N-(1-Oxo-1H-inden-2-yl)benzamides Catalyzed by HPW@nano-SiO(2) under Microwave Irradiation

[摘要]：A facile, efficient, and large-scale strategy for the synthesis of N-(1-oxo-1H-inden-2-yl)benzamide derivatives via domino reaction between aryl aldehydes, hippuric acid, and acetic anhydride catalyzed by HPW@nano-SiO(2) was accomplished under microwave irradiation. The reaction conditions are very simple and offer easy isolation of the product. Moreover, the catalyst can be reused up to five times in 86% average yield after simple filtration.

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