[摘要]：The 1,3-dipolar cycloaddn. of pyrimidinealdoxime-derived nitrile oxides and alkynes delivers 4-(isoxazol-3-yl)pyrimidines. This procedures accommodates 3 points of diversification around this bisheterocyclic scaffold, and the resulting compd. library was added to the NIH repository for pilot-scale biomedical studies. The compds. exhibited poor insecticidal activity.
