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THREE NEW IRIDOID COMPOUNDS FROM SWERTIA CINCTA BURKILL

  作者 YANG JIN; HUANG FEIYAN; ZHOU YONGFU; LIU WEI; YI PING; LI GANPENG  
  选自 期刊  Heterocycles;  卷期  2012年85-11;  页码  2775-2780  
  关联知识点  
 

[摘要]Three new iridoid compounds, 3,4,5,6-tetrahydro-8-hydroxy-6-(hydroxymethyl)pyrano[3,4-c]pyran-1(8H)-one (1), 3,4,5,6-tetrahydro-8-hydroxy-6-methylpyrano[3,4-c]pyran-1(8H)-one (2), 5,6-dihydro-4-(1,3-dihydroxybutan-2-yl)-3-(hydroxymethyl)pyran-2-one (3), named swercinctolides A, B and C, were isolated from the 80% methanol extract of the whole plant of Swertia cincta Burkill, which is a traditional medicine in China. Their structures were defined on the basis of spectral evidences. Compounds 1, 2 and 3 showed TMV (Tobacco Mosaic Virus) inhibitory activity.

 
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