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Consecutive Condensation, C-N and N-N Bond Formations: A Copper- Catalyzed One-Pot Three-Component Synthesis of 2H-Indazole

  作者 KUMAR MANIAN RAJESH; PARK AHBYEOL; PARK NAMJIN; LEE SUNWOO  
  选自 期刊  Organic Letters;  卷期  2011年13-13;  页码  3542-3545  
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[摘要]2H-Indazoles are synthesized using copper-catalyzed, one-pot, three-component reactions of 2-bromobenzaldehydes, primary amines, and sodium azide. A copper catalyst plays the key role in the formation of C-N and N-N bonds. This method has a broad substrate scope with a high tolerance for a variety of functional groups.

 
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