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Mild Nonepimerizing N-Alkylation of Amines by Alcohols without Transition Metals

  作者 GUERIN CLAIRE; BELLOSTA VERONIQUE; GUILLAMOT GERARD; COSSY JANINE  
  选自 期刊  Organic Letters;  卷期  2011年13-13;  页码  3534-3537  
  关联知识点  
 

[摘要]A one-pot two-step sequence involving an oxidation/imine-iminium formation/reduction allowed the N-alkylation of amines by alcohols without any epimerization when optically active alcohols and amines are involved in the process.

 
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