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Yalongenes A and B, Two New Cembranoids with Cytoprotective Effects from the Hainan Soft Coral Sarcophyton trocheliophorum Marenzeller

  作者 Yao, LG; Zhang, HY; Liang, LF; Guo, XJ; Mao, SC; Guo, YW  
  选自 期刊  Helvetica Chimica Acta;  卷期  2012年95-2;  页码  235-239  
  关联知识点  
 

[摘要]Two new cembranoids, yalongenes A (1) and B (2), were isolated from the South China Sea soft coral Sarcophyton trocheliophorum Marenzeller. Their structures were elucidated by detailed spectroscopic analysis (IR, MS, and NMR) and by comparison with a related model compound. Yalongenes 1 and 2 were evaluated for their cytoprotective effects on SH-SY5Y cell injury induced by H2O2 in vitro, and the result showed that only compound 1 had a significant cytoprotective activity at the concentration of 1 mu M.

 
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