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Microwave-Assisted Copper-Catalyzed Cross-Coupling Reaction of Alkynes with Aryl Iodides and Vinyl Halides

  作者 TSAI WENTING; LIN YUNYUNG; WANG YUJEN; LEE CHINFA  
  选自 期刊  Synthesis;  卷期  2012年44-10;  页码  1507-1510  
  关联知识点  
 

[摘要]The microwave-assisted, copper-catalyzed coupling of terminal alkynes with aryl iodides and vinyl halides is reported. In general, the reactions are completed in 10-30 min using 2-5 mol% [CuI(xantphos)] as a catalyst to provide the corresponding alkynes and enynes in good to excellent yields. A broad spectrum of aryl iodides, vinyl iodides, and bromides are coupled with aryl- and alkyl alkynes.

 
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