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A Concise Asymmetric Synthesis of (-)-Hongconin and (-)-1-epi-Hongconin

  作者 FERNANDES RODNEY A; CHAVAN VIJAY P  
  选自 期刊  European Journal of Organic Chemistry;  卷期  2010年-22;  页码  4306-4311  
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[摘要]A concise asymmetric synthesis of (-)-hongconin and (-)-1-epi-hongconin is described The synthesis features an efficient combination of Dotz benzannulation or lactaldehyde arylation and the oxa-Pictet-Spengler reaction as the key steps The synthesis is completed in 10-11 steps from the chiral pool material (R)-methyl lactate

 
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