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A label-free electrical detection of exosomal microRNAs using microelectrode array

  作者 GODA TATSURO; MASUNO KOZUE; NISHIDA JUNKO; KOSAKA NOBUYOSHI; OCHIYA TAKAHIRO; MATSUMOTO AKIRA; MIYAHARA YUJI  
  选自 期刊  Chemical Communications;  卷期  2012年48-98;  页码  11942-11944  
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[摘要]We report a method for detecting microRNAs encapsulated in exosomes using a microelectrode array in semiconductor-based potentiometry after RT-PCR. The inherent miniaturization of the electrical biosensor meets requirements for massively parallel analysis of circulating microRNA as a noninvasive biomarker.

 
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