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The RAF Inhibitor Paradox Revisited

  作者 Cox, AD; Der, CJ  
  选自 期刊  Cancer Cell;  卷期  2012年21-2;  页码  147-149  
  关联知识点  
 

[摘要]The success of the RAF protein kinase inhibitor vemurafenib for the treatment of BRAF mutant metastatic melanoma has produced another poster child for the promise of personalized medicine. However, the results of a recent study also reveal unexpected pitfalls in the application of signal transduction-targeted therapies.

 
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