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NEW DIHYDROAGAROFURANOID SESQUITERPENES FROM CELASTRUS ANGULATUS

  作者 LIU JIANGYUN; TAN BEIBEI; GONG XUELONG; XU QIONGMING; SUN XIAOFEI; CAI PEILIE; YANG SHILIN  
  选自 期刊  Heterocycles;  卷期  2012年85-3;  页码  689-696  
  关联知识点  
 

[摘要]Three new highly esterified beta-dihydroagarofuran sesquiterpenes (1-3) were isolated from the root barks of Celastrus angulatus Max. together with eight (4-11) known ones. The new compounds were identified as 1 beta-picolinoyloxy-2 beta,6 alpha-diacetoxy-8 beta,13-diisobutanoyloxy-9 alpha-benzoyloxy-4 alpha-hydroxy-beta-dihydro- agarofuran (I), 1 beta-picolinoyloxy-2 beta,6 alpha-diacetoxy-8 beta,13-diisobutanoyloxy-9 alpha-furanoyloxy-4 alpha-hydroxy-beta-dihydroagarofuran (2), and 1 beta,6 alpha-diacetoxy-2 beta-nicotinoyloxy-8 beta,13-diisobutanoyloxy-9 alpha-benzoyloxy-4 alpha-hydroxy-beta-dihydro- agarofuran (3) on the basis of spectroscopic methods. Compounds 1-11 were all possessed cytotoxic activities against three human tumor cell lines by MTT assay.

 
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