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Synthesis of cycloalkanoindoles, the carba analogs of physostigmine.

  作者 Kiraly, Imre;Hornyanszky, Gabor;Kupai, Katalin;Novak, Lajos;  
  选自 期刊  Heterocycles;  卷期  2008年75-1;  页码  43-56  
  关联知识点  
 

[摘要]The title compds. I (n = 0-1) were prepd. by combined aza-Claisen rearrangement/intramol. ring-closure reaction of appropriate N-(cycloalk-1-enylmethyl)-4-methoxyanilines, followed by BBr3-mediated cleavage of methoxy group, and subsequent formation of the phenylcarbamyl derivs.

 
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