Synthesis and Antimicrobial Activity of 4-(10H-Phenothiazin-2-yl)-pyrimidin-2(1H)-one/thione Derivatives

[摘要]：A series of chalcones 3a-d containing phenothiazine nucleus were prepared by Claisen-Schmidt condensation. The chalcones on treatment with urea, thiourea, phenyl urea, and phenyl thiourea in alcoholic KOH yielded compounds 4a-p, and the structures of these compounds were confirmed by spectral and elemental analyses. The newly synthesized compounds were evaluated for antimicrobial activity.

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