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A Versatile Synthetic Extracellular Matrix Mimic via Thiol-Norbornene Photopolymerization

  作者 Fairbanks, BD; Schwartz, MP; Halevi, AE; Nuttelman, CR; Bowman, CN; Anseth, KS  
  选自 期刊  ADVANCED MATERIALS;  卷期  2009年21-48;  页码  5005-5005  
  关联知识点  
 

[摘要]Step-growth, radically mediated thiol-norbornene photopolymerization is used to create versatile, stimuli-responsive poly(ethylene glycol)-co-peptide hydrogels (see image). The reaction is cytocompatible and allows for the encapsulation of human mesenchymal stem cells with a viability greater than 95%. Cellular spreading is dictated via three-dimensional biochemical photopatterning.

 
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