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[F-18]Fluorination of an arylboronic ester using [F-18]selectfluor bis(triflate): application to 6-[F-18]fluoro-L-DOPA

  作者 STENHAGEN IDA S R; KIRJAVAINEN ANNA K; FORSBACK SARITA J; JORGENSEN CHARLOTTE G; ROBINS EDWARD G; LUTHRA SAJINDER K; SOLIN OLOF; GOUVERNEUR VERONIQUE  
  选自 期刊  Chemical Communications;  卷期  2013年49-14;  页码  1386-1388  
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[摘要]The Ag-mediated electrophilic [F-18]fluorination of an arylboronic ester is reported. This new radiochemical transformation uses [F-18]selectfluor bis(triflate) in acetone. The process gave 6-[F-18]-fluoro-L-DOPA with a RCY of 19 +/- 12% and a specific activity of 2.6 +/- 0.3 GBq mu mol(-1).

 
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