Template-induced enantioselectivity in the reductive radical cyclization of 3-(3-iodopropoxy)propenoic acid derivatives depending on the binding motif.

[摘要]：Different binding motifs HXC:O were screened in the enantioselective radical cyclization of various linear derivs. of 3-(3-iodopropoxy)propenoate. The reactions were performed in the presence of an enantiomerically pure, chiral 1,5,7-trimethyl-3-azabicyclo[3.3.1]nonan-2-one, which acts as a hydrogen-binding template. The cyclized products were obtained in good to excellent yields (66-88%). Enantioselectivities of ?9% ee were achieved.

[全文传递流程]：

一般上传文献全文的时限在1个工作日内