[摘要]：A new prenylated isoflavonoid, flemiphilippinin G (1), and a new flavonol glycoside, flemiphilippininside (2), along with eleven known isoflavonoids were obtained from the roots of Flemingia philippinensis (Merr. et Rolfe) Li. Their structures were elucidated on the basis of spectroscopic data. The in vitro cytotoxicities of compounds 113 against MCF-7, A549, and Hep-G2 cell lines were determined by using the MTT (=3-(4,5-dimethylthazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide) colorimetric assay, and their antioxidant activities were evaluated by ferric-reducing antioxidant power (FRAP) method. Compound 1 exhibited significant cytotoxicity against all the tested cell lines with IC50 values of 4.87.3 mu M, and compound 2 was found to be inactive. Both compounds 1 and 2 showed weak antioxidant activities with FRAP values of 110+/-15 and 124+/-16 mu mol/g, respectively.
