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Copper-Catalyzed Direct Arylation of Cyclic Enamides Using Diaryliodonium Salts

  作者 GIGANT NICOLAS; CHAUSSETBOISSARIEI LAETITIA; BELHOMME MARIECHARLOTTE; POISSON THOMAS; PANNECOUCKE XAVIER; GILLAIZEU ISABELLE  
  选自 期刊  Organic Letters;  卷期  2013年15-2;  页码  278-281  
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[摘要]A convenient method for the copper(II)-catalyzed direct arylation of cyclic and nonaromatic enamides using diaryliodonium salts has been developed. The reaction demonstrates large functional group tolerance, good yields, and total regioselectivity with a C(3)-functionalization. The synthetic potential of this coupling was explored by using a range of readily accessible diaryliodonium salts and enamides.

 
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