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Stereoselective Synthesis of Functionalized Cyclopropane Derivatives via alpha-Thiocyanate Ketone-Based Three-Component Reaction

  作者 WU FEIYUE; LI YING; FENG HUI; WU QIONG; JIANG BO; SHI FENG; TU SHUJIANG  
  选自 期刊  Synthesis;  卷期  2011年-15;  页码  2459-2465  
  关联知识点  
 

[摘要]alpha-Thiocyanate ketone-based three-component reactions have been established for the stereoselective synthesis of functionalized electron-deficient trans-cyclopropanes. The multicomponent reactions were conducted by reacting readily available and inexpensive starting materials under microwave irradiation. The procedures are very facile, highly stereoselective, and avoids the use of ylides.

 
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