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Convenient syntheses of 2-alkyl(aryl)-4,5-diphenyloxazoles and 2-alkyl(aryl)-4-phenyloxazoles

  作者 Pei, WW; Li, SH; Nie, XP; Li, YW; Pei, J; Chen, BZ; Wu, J; Ye, XL  
  选自 期刊  Synthesis;  卷期  1998年-9;  页码  1298-1304  
  关联知识点  
 

[摘要]The synthetic methods to prepare 2-alkyl(aryl)-4,5-diphenyloxazoles and 2-alkyl(aryl)-4-phenyloxazoles were improved on the basis of a mechanistic study of oxazole formation from alpha-hydroxy ketones (carboxylic esters of benzoin and phenacyl alcohols). By these methods, seven trisubstituted oxazoles and twelve disubstituted oxazoles of the title compounds were prepared.

 
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