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Novel N,S-phenacyl protecting group and its application for peptide synthesis.

  作者 Tang, Guo;Ji, Tao;Hu, An-Fu;Zhao, Yu-Fen;  
  选自 期刊  SYNLETT;  卷期  2008年-12;  页码  1907-1909  
  关联知识点  
 

[摘要]The phenacyl group can be introduced onto amino and thio groups by N,S-alkylation reactions. Conversely, these groups are removed rapidly by employing magnesium in acetic acid. This protecting group was successfully applied to a short peptide synthesis of Boc-L-Cys-Gly-OMe.

 
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