Tris(pentafluorophenyl)borane-catalyzed three-component reaction for the synthesis of 1,8-dioxodecahydroacridines under solvent-free conditions.

[摘要]：A mild and efficient method for the synthesis of 1,8-dioxodecahydroacridines was developed. The synthesis proceeds via a three-component reaction of a 1,3-dione, an aldehyde, and an amine, under solvent-free conditions, catalyzed by tris(pentafluorophenyl)borane [B(C6F5)3]. The mildness of the catalyst was demonstrated by studying the reaction of 1,3-cyclohexanedione with various aldehydes and amines which gave the 1,8-dioxo-decahydroacridines in high yields.

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